Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8452784 | Hematology/Oncology and Stem Cell Therapy | 2018 | 10 Pages |
Abstract
A chronic hypercoagulable state and platelet activation is present in children with β-thalassemia. Splenectomy and transfusion infrequency are the main risk factors noted to be associated with such hypercoagulable state and platelet activation and consequently the PH among our thalassemic patients.
Keywords
MTHFRHLPCPASPmPAPTRVRVOTRBCRed blood cellsThalassemiathalassemia majorThromboembolismThromboembolicBlood transfusionhypercoagulable statepulmonary artery systolic pressuremean pulmonary artery pressurePlatelet activationmethylene tetrahydrofolate reductaseRight ventricular outflow tractPulmonary hypertensionhigh-performance liquid chromatography
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Authors
Mahmoud Alhosiny Fayed, Hesham El-Sayed Abdel-Hady, Mona Mohammed Hafez, Osama Saad Salama, Youssef Abdelhalim Al-Tonbary,