| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8453318 | Leukemia Research | 2018 | 6 Pages |
Abstract
Our results could indicate a clinically relevant relationship between MDS and OSP in elderly patients, most likely resulting from a disturbed microenvironment within the osteo-hematopoietic niche. An alternative, non-causal explanation that MDS is caused by the medication prescribed for OSP can be partially ruled out, as the association between the two diseases remains if incident OSP cases are considered in patients with pre-existing MDS. These results need to be confirmed within other prospective studies and may allow then for comprehensive strategies for the prevention, early detection and clinical care of patients with MDS and OSP.
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Authors
Thomas Datzmann, Freya Trautmann, Falko Tesch, Anna Mies, Lorenz C. Hofbauer, Uwe Platzbecker, Jochen Schmitt,