Article ID Journal Published Year Pages File Type
8453422 Leukemia Research 2017 6 Pages PDF
Abstract
The present study found that a new DAS resistance pathway of EphB4 overexpression was triggered by EphrinB2-Fc, which induced the resistance to DAS by activating RhoA/ROCK1/PTEN/MCL-1 signaling.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Distinct EphB4-mediated mechanisms of apoptotic and resistance to dasatinib in human chronic myeloid leukemia and K562 cell lines
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