Article ID Journal Published Year Pages File Type
8453565 Lung Cancer 2018 5 Pages PDF
Abstract
This report presents the first case with two novel gene mutations of the WDFA, suggesting that in addition to β-catenin, BRCA2 and TSC2 might play some important roles in up-regulation of Wnt signaling pathway. Moreover, use of NGS technique is helpful to understand the biology of this rare neoplasm and provide the potential gene for targeted therapy.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
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