| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8453577 | Lung Cancer | 2018 | 8 Pages |
Abstract
In NSCLC with RTD, ICPi have favorable efficacy and independent impact on OS. NSCLC with RTD is associated with MSI stable status and variable levels of PD-L1 expression and TMB; their predictive value remains to be determined.
Keywords
PD-L1PET-CTBRAFROS1MSITMBECoGcMETTPsv-raf murine sarcoma viral oncogene homolog BMSI-HRTDORRICPIPD-1MutSC-ros oncogene 1EGFRPFsALKimmunotherapyIHCImmunohistochemistryTumor mutational burdenprogression-free survivaloverall survivalMicrosatellite instabilitymicrosatellite instability-highcomputer tomographymutationmutationsRETLung cancerNSCLCNon-small cell lung cancerAnaplastic lymphoma kinaseprogrammed cell death ligand-1Programmed cell death-1objective response rateEpidermal growth factor receptor
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Authors
Elizabeth Dudnik, Elias Bshara, Ahuva Grubstein, Ludmila Fridel, Tzippy Shochat, Laila C. Roisman, Maya Ilouze, Anna Belilovski Rozenblum, Smadar Geva, Alona Zer, Ofer Rotem, Aaron M. Allen, Nir Peled,