| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8455461 | Matrix Biology | 2014 | 9 Pages |
Abstract
The extracellular matrix composition changes dramatically during the development of lung fibrosis. The increased levels of elastin, type V collagen and tenascin C are probably the result of increased expression by fibroblastic cells; reversely, elastin influences myofibroblast differentiation. This suggests a reciprocal interaction between fibroblasts and the extracellular matrix composition that could enhance the development of lung fibrosis.
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Authors
Marjolein E. Blaauboer, Fee R. Boeijen, Claire L. Emson, Scott M. Turner, Behrouz Zandieh-Doulabi, Roeland Hanemaaijer, Theo H. Smit, Reinout Stoop, Vincent Everts,