| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8455725 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2015 | 8 Pages |
Abstract
- B[a]P phosphorylated phospho-Chk1 via p-ERK.
- P-ERK promoted to p-c-Myc bind to E-box response element.
- Phospho-Chk1 activated p-p53 and induced S-phase accumulation.
Keywords
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![Benzo[a]pyrene-induced cell cycle progression occurs via ERK-induced Chk1 pathway activation in human lung cancer cells](/preview/png/8455725.png "First Page Preview: Benzo[a]pyrene-induced cell cycle progression occurs via ERK-induced Chk1 pathway activation in human lung cancer cells")
Authors
Bing-Yen Wang, Sung-Yu Wu, Sheau-Chung Tang, Chien-Hung Lai, Chu-Chyn Ou, Ming-Fang Wu, Yi-Min Hsiao, Jiunn-Liang Ko,