| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8455773 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2014 | 9 Pages |
Abstract
- We have applied telomere and centromere (TC) staining to the scoring of dicentrics.
- TC staining renders the scoring of dicentrics more rapid and robust.
- TC staining allows the scoring of not only dicentrics but all chromosomal anomalies.
- TC staining has led to a reevaluation of the radiation dose-response curve.
- TC staining allows automation of the scoring of chromosomal aberations.
- Automated scoring of dicentrics after TC staining was as efficient as manual scoring.
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Authors
Radhia M'kacher, Elie E.L. Maalouf, Michelle Ricoul, Leonhard Heidingsfelder, Eric Laplagne, Corina Cuceu, William M. Hempel, Bruno Colicchio, Alain Dieterlen, Laure Sabatier,