Article ID Journal Published Year Pages File Type
8455784 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2014 8 Pages PDF
Abstract

- In vivo effects of docetaxel doses were monitored to identify energy of those doses.
- Energy was perfectly correlated with dose in the optimal standard regimens (OSR).
- Dose-energy model with perfect fit was established for docetaxel therapy in OSR.
- Administered dose should be patient-specific and sufficient for the suggested regimen.
- Time to 2nd dose delivery in OSR is less than twice the tumor doubling time intraday.
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