Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8455841 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2014 | 14 Pages |
Abstract
In this review, we present a hypothesis that the bacterial infection, exposure to heat-killed bacteria or even some bacterial determinants may trigger genome instability of exposed and distal cells, and thus may cause cancer. We will discuss the mechanisms of host responses to the bacterial infection and present the possible pathways leading to genome instability and cancer through exposure to bacteria.
Keywords
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Olga Kovalchuk, Paul Walz, Igor Kovalchuk,