| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8455864 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2013 | 9 Pages |
Abstract
âºDNA methylation in 200 children from two regions in the Czech Republic was analyzed. ⺠Both regions differed in concentrations of air pollutants. ⺠The Human Methylation 27K BeadChips were used in this study. ⺠An impact of different environmental conditions on DNA methylation was found. ⺠Gender, cotinine, and pregnancy-related factors affected DNA methylation.
Keywords
LBWLong interspersed nucleotide element-1CYP1A1Sat2Gfi1ACSL3PLSTCDDAHRRPCBsADRB2iNOSIFNγVLBW2,3,7,8-tetrachlorodibenzodioxin5-mC5-methyl-cytosineB[a]PPCABronchial asthmaPOPsPersistent organic pollutantsAir pollutionSINEinterferon γBenzo[a]pyrenePolychlorinated biphenylsPrincipal component analysispartial least squareLINE-1particulate matterinducible nitric oxide synthasecytochrome P450 1A1Polycyclic aromatic hydrocarbonsPAHsVery low birth weightLow birth weightChildrenBeta-2 adrenergic receptoraryl hydrocarbon receptor repressor
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Authors
Andrea Rossnerova, Elena Tulupova, Nana Tabashidze, Jana Schmuczerova, Miroslav Dostal, Pavel Rossner Jr, Hans Gmuender, Radim J. Sram,