Article ID Journal Published Year Pages File Type
8455885 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2012 9 Pages PDF
Abstract
► Exposure to gamma irradiation increased the expression of bax. ► Exposure to gamma irradiation decreased the expression of bcl-2. ► Melatonin pretreatments reduced the percentage of apoptotic lymphocytes. ► Melatonin pretreatments modified the expression of bax and bcl-2. ► Melatonin pretreatment may improve the therapeutic index in radiation oncology.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Preview
Melatonin may play a role in modulation of bax and bcl-2 expression levels to protect rat peripheral blood lymphocytes from gamma irradiation-induced apoptosis
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