Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8455918 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2012 | 8 Pages |
Abstract
⺠Telomere proteins participate in telomere protection, replication and length regulation. ⺠Mammalian telomeres are protected by the shelterin complex. ⺠Telomeres may switch between closed, protected and open, replication-competent states. ⺠Telomere replication is a multi-step process that involves telomerase, CST and shelterin. ⺠Defects in telomere replication and loss of telomere protection can impact human health.
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Authors
Jason A. Stewart, Mary F. Chaiken, Feng Wang, Carolyn M. Price,