Article ID Journal Published Year Pages File Type
8455918 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2012 8 Pages PDF
Abstract
► Telomere proteins participate in telomere protection, replication and length regulation. ► Mammalian telomeres are protected by the shelterin complex. ► Telomeres may switch between closed, protected and open, replication-competent states. ► Telomere replication is a multi-step process that involves telomerase, CST and shelterin. ► Defects in telomere replication and loss of telomere protection can impact human health.
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