Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8455940 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2012 | 10 Pages |
Abstract
⺠Telomere crisis implicated as a common crucial event in malignant transformation. ⺠Telomere length has emerged as a putative biomarker of cancer disease risk. ⺠Estimates from prospective studies are much weaker than from retrospective studies. ⺠Differences may be due to biases intrinsic to retrospective study design. ⺠Study design considerations are given for future investigations.
Keywords
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Cancer Research
Authors
Jennifer Prescott, Ingrid M. Wentzensen, Sharon A. Savage, Immaculata De Vivo,