| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8455946 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2012 | 8 Pages |
Abstract
⺠Telomerase is a universal cancer therapeutic target. ⺠Telomerase confers limitless replicative potential to cancer cells, a hallmark of cancer. ⺠Telomerase inhibitors are currently in clinical trials: Imetelstat, a direct telomerase antagonist; Gene therapy targeting telomerase expressing cells; Immunotherapy targeting telomerase specific peptides.
Keywords
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
C.M. Buseman, W.E. Wright, J.W. Shay,