Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456107 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2008 | 8 Pages |
Abstract
DNA-SSB and DSB in PBLs are present in cancer patients before treatment and increase significantly after combined chemotherapy. No correlation with response to adjuvant chemotherapy was found. Biomonitoring DNA damage in PBLs of cancer patients could help prevent secondary effects and the potential risks of developing secondary cancers.
Keywords
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Patricia Sánchez-Suárez, Patricia Ostrosky-Wegman, Francisco Gallegos-Hernández, Rubicelia Peñarroja-Flores, Jorge Toledo-GarcÃa, José Luis Bravo, Emilio Rojas del Castillo, Luis BenÃtez-Bribiesca,