Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456158 | Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis | 2008 | 4 Pages |
Abstract
Our work provides the first in vivo evidence suggesting that increased levels of 8-oxodG in DNA may lead to carcinogenesis not only via mispair/mutagenic potential of the modified base but also through its ability to influence gene expression by affecting DNA methylation.
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Jolanta Guz, Marek Foksinski, Agnieszka Siomek, Daniel Gackowski, Rafal Rozalski, Tomasz Dziaman, Anna Szpila, Ryszard Olinski,