Article ID Journal Published Year Pages File Type
8456158 Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis 2008 4 Pages PDF
Abstract
Our work provides the first in vivo evidence suggesting that increased levels of 8-oxodG in DNA may lead to carcinogenesis not only via mispair/mutagenic potential of the modified base but also through its ability to influence gene expression by affecting DNA methylation.
Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
Authors
, , , , , , , ,