Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456412 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2015 | 4 Pages |
Abstract
These results indicate that the repeated-dose liver micronucleus assay allowed for the detection of micronucleus induction by DAB, and that the lowest detectable dose for micronucleus induction in the liver was lower than in the bone marrow. Thus, the repeated-dose liver micronucleus assay using young adult rats is considered suitable for the detection of micronucleus induction by liver carcinogens, such as DAB.
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Authors
Yasushi Shimada, Hajime Sui, Yumi Wako, Kazufumi Kawasako,