Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456423 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2015 | 6 Pages |
Abstract
Kojic acid has been known to act as a tumor-promoter in thyroid carcinogenesis but has not been shown to have initiation activities in liver carcinogenesis. Findings in this study are consistent with the evidence that kojic acid is not an apparent initiator of liver carcinogenesis. Therefore, the liver micronucleus assay is simple and sensitive to detect genotoxic liver carcinogens.
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Authors
Yosuke Ogiwara, Mihoko Sugiura, Kumiko Watanabe, Junko Tawara, Emi Endo, Hiromi Maruyama, Satoshi Tsuji, Kenta Matsue, Hisaharu Yamada, Yumi Wako, Kazufumi Kawasako,