| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456455 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2014 | 5 Pages |
Abstract
The increasing use of nanotechnologies will lead to significant releases of engineered nanoparticles into the aquatic environment, where their impact is still poorly characterized. In the present paper, the genotoxic and cytotoxic properties of CdS quantum dots (QDs) and silver sulphide (Ag2S) coated with methyl polyethylene glycol (M-PEG) were investigated in a rainbow trout cell line (RTG-2). The results showed that CdS QDs were highly cytotoxic at high concentrations (10 and 50 μg/ml), and exhibited a concentration-dependent genotoxicity in the sub-toxic range (0.01-1 μg/ml) after 24 h exposure. Ag2S showed neither genotoxic nor cytotoxic effects.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Marco Munari, Joachim Sturve, Giada Frenzilli, Matthew B. Sanders, Andrea Brunelli, Antonio Marcomini, Marco Nigro, Brett P. Lyons,