Article ID Journal Published Year Pages File Type
8456515 Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2013 7 Pages PDF
Abstract
We hypothesise that the ring chromosome 8 has been developed during the 5 FU/folic acid treatments in 2003. The long term persistence might be due to clonal expansion of a damaged but viable hematopoietic stem cell giving rise to cycling progenitor cells that permit cell survival and proliferation.
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Related Topics
Life Sciences Biochemistry, Genetics and Molecular Biology Cancer Research
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Persisting ring chromosomes detected by mFISH in lymphocytes of a cancer patient-A case report
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