| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456542 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2013 | 8 Pages |
Abstract
⺠Black soybean seed coat extract (BE) inhibited B(a)P-induced genotoxicity. ⺠Cyanidin 3-glucoside and procyanidins in BE contributed to the anti-genotoxicity. ⺠Cyanidin 3-glucoside and procyanidins decreased B(a)P-induced CYP1A1 expression. ⺠Cyanidin 3-glucoside and procyanidins increased GSTs expression.
Keywords
nuclear factor-erythroid-2-related factor 2AHRMN assayNrf2GSTCytochrome P4501A1DREC3GCYP1A1(−)-epicatechinB(a)PMicronucleus assayElectrophoretic mobility shift assayDNA damageBenzo[a]pyreneEMSA یا electrophoretic mobility shift assay Cyanidin 3-glucosideantioxidant response elementsdioxin responsive elementAREProcyanidinglutathione S-transferaseGlutathione S-transferase (GST)aryl hydrocarbon receptor
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Authors
Tianshun Zhang, Songyan Jiang, Chao He, Yuki Kimura, Yoko Yamashita, Hitoshi Ashida,