| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456572 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2012 | 7 Pages |
Abstract
⺠Different sized gold nanoparticles were instilled once to lungs of male Wistar rats. ⺠The Comet assay showed no increased DNA damage in lung cells. ⺠The micronucleus rate in bone marrow cells was not adversely affected. ⺠There were neither relevant clinical nor histopathological findings.
Keywords
NCEWPMNin vivo genotoxicityICRPEFSAPCEROSMicronucleus testEuropean Food Safety Authoritynormochromatic erythrocytepolychromatic erythrocyteTemBALFInstillationComet assayBronchoalveolar lavage fluidTransmission electron microscopyNanoparticleGold nanoparticlesInternational Commission on Radiological ProtectionReactive oxygen species
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Authors
Markus Schulz, Lan Ma-Hock, Sandra Brill, Volker Strauss, Silke Treumann, Sibylle Gröters, Bennard van Ravenzwaay, Robert Landsiedel,