Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456578 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2012 | 8 Pages |
Abstract
⺠Mice exposed to 50 and 300 mg/kg b.wt., ZnO NPs through oral route for 14 consecutive days. ⺠The mice revealed elevated ALT and ALP serum levels and accumulation of NPs in liver with subsequent pathological lesions. ⺠ZnO NPs induced oxidative stress in the mice liver and kidney as indicated by an increase in LPO. ⺠The ZnO NPs induced oxidative stress led to DNA damage and apoptosis in the mice liver.
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Authors
Vyom Sharma, Poonam Singh, Alok K. Pandey, Alok Dhawan,