Article ID Journal Published Year Pages File Type
8456578 Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2012 8 Pages PDF
Abstract
► Mice exposed to 50 and 300 mg/kg b.wt., ZnO NPs through oral route for 14 consecutive days. ► The mice revealed elevated ALT and ALP serum levels and accumulation of NPs in liver with subsequent pathological lesions. ► ZnO NPs induced oxidative stress in the mice liver and kidney as indicated by an increase in LPO. ► The ZnO NPs induced oxidative stress led to DNA damage and apoptosis in the mice liver.
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