| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456605 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 7 Pages |
Abstract
⺠Radioprotection of mouse splenocytes by Ganoderma triterpenes was examined in vitro. ⺠Total triterpenes were effective in preventing DNA damage and ladder formation. ⺠It reduced the percentage of apoptotic cells as revealed by flow cytometric assay. ⺠It decreased intracellular ROS generation and enhanced endogenous antioxidant status. ⺠The findings suggest its therapeutic use as an ideal radio protector in radiotherapy.
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Authors
T.P. Smina, Strayo De, T.P.A. Devasagayam, S. Adhikari, K.K. Janardhanan,