Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456608 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 9 Pages |
Abstract
⺠3-OHAA in the presence of copper could cause single stranded nicks in the DNA. ⺠3-OHAA in the presence of metal cofactor copper causes mutagenic effect in TA102. ⺠The presence of liver S9 detoxifies the mutagenic effect of 3-OHAA and copper. ⺠AA in the presence of copper does not cause any mutagenic effect. ⺠Both AA and 3-OHAA do not cause any mutagenic effect by themselves.
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Authors
Gopi S. Gadupudi, King-Thom Chung,