| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456611 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 7 Pages |
Abstract
⺠Genotoxic effects of IPA in D. melanogaster were evaluated in germ and somatic cells. ⺠IPA induced up to 50 fold increase of ND in offspring born in the 24 h post treatment. ⺠In larvae, 50% IPA increased spots/100 eyes but the response is not dose-dependent. ⺠IPA failed to induce SLRL in any of the spermatogenesis stages tested. ⺠IPA effect probably is not on DNA directly but it perturbs nuclear membrane.
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Authors
Ana MarÃa Palermo, Marta Dolores Mudry,