| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456613 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 5 Pages |
Abstract
⺠We show in vivo induction of oxidative DNA damage by H2O2, CdCl2 and CuSO4 in Drosophila melanogaster. ⺠We show in vivo detection of oxidative DNA damage by modified alkaline Comet assay using FPG/ENDOIII in Drosophila. ⺠D. melanogaster is recommended as a sensitive and suitable in vivo model for detecting oxidative DNA damage under genotoxicity assessment of chemicals.
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Authors
A.K. Shukla, P. Pragya, D. Kar Chowdhuri,