Article ID Journal Published Year Pages File Type
8456622 Mutation Research/Genetic Toxicology and Environmental Mutagenesis 2011 12 Pages PDF
Abstract
► Two extraction procedures were compared to assess genotoxicity of sediments of the Berre lagoon. ► Organic mutagens were extracted by hexane/dichloromethane and 2-propanol. ► Genotoxicity was evaluated by the Ames test, the comet and the micronucleus assays. ► Extraction by hexane/dichloromethane mainly selected non-polar mutagens (PAHs). ► Extraction by 2-propanol mainly selected polar mutagens (aromatic amines and nitro arenes).
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Preview
Comparison of two extraction procedures for the assessment of sediment genotoxicity: Implication of polar organic compounds
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