Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8456629 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 7 Pages |
Abstract
⺠We investigates the effects of CLb on cDDP-induced DNA damage and oxidative stress. ⺠We used micronucleus test and comet assay to asses DNA damage. ⺠TBARS, CAT and GSH levels were used to assess oxidative stress. ⺠CLbreduced the cDDP-induced genotoxicity ⺠Lipid peroxidation induced by cDDP was strongly attenuated by CLb.
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Authors
Juliana Mara Serpeloni, Denise Grotto, Alexandre Ferro Aissa, Adriana Zerlotti Mercadante, Maria de Lourdes Pires Bianchi, Lusânia Maria Greggi Antunes,