| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8456647 | Mutation Research/Genetic Toxicology and Environmental Mutagenesis | 2011 | 7 Pages |
Abstract
⺠Enormous efforts have been directed, towards developing an agent to protect man and other life forms from deleterious effects of ionizing radiation. ⺠Alpha-lipoic acid an important biomolecule, participating as a prosthetic group in various important cellular enzymatic reactions, having high antioxidant activity was explored for its protective effects on ionizing radiation induced genotoxic damages by employing plasmid relaxation, comet, micronucleus and chromosomal aberration assays. ⺠We conclude that lipoic acid could be used as a safe and non-toxic radioprotector against radiation exposure scenarios.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
Authors
Lakshmy Ramachandran, Cherupally Krishnan Krishnan Nair,