| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457416 | Neurologia i Neurochirurgia Polska | 2017 | 4 Pages |
Abstract
Low concentration of valproic acid after administration the slow-released tablets are usually observed. However, a low bioavailability beside the bad compliance should be considered when the minimal level is extremely low during therapy. It is known that form of the drug, beside presence of food and its components, as well as gastrointestinal tract condition or interactions with other drugs can influence the drug level. Modification of the formulation of the drug may lead to improvement of absorption and increase its effectiveness.
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Authors
Anna Jopowicz, Agnieszka Piechal, Iwona Kurkowska-JastrzÄbska,