Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8457584 | Nuclear Medicine and Biology | 2018 | 43 Pages |
Abstract
Use of this brush border enzyme-cleavable linker reduced kidney uptake and resulted in improved tumor:kidney uptake ratios. Although further structural improvements are needed, this linker approach might be useful as a component in strategies for reducing renal uptake of radiolabeled PSMA inhibitors.
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Authors
Ganesan Vaidyanathan, Choong Mo Kang, Darryl McDougald, Il Minn, Mary Brummet, Martin G. Pomper, Michael R. Zalutsky,