Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8457600 | Nuclear Medicine and Biology | 2018 | 8 Pages |
Abstract
A new ligand has been developed and radiolabeled with Al[18F]F that allows rapid (50-min) preparation of fluorine-18 serum albumin in one-pot. In addition to increased synthetic efficiency, the construct appears to be metabolically stable in rats. This method could encourage wider use of PET to quantify cardiac function and tissue vascular integrity in both research and clinical settings.
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Authors
Falguni Basuli, Xiang Zhang, Mark R. Williams, Jurgen Seidel, Michael V. Green, Peter L. Choyke, Rolf E. Swenson, Elaine M. Jagoda,