| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457721 | Nuclear Medicine and Biology | 2018 | 39 Pages |
Abstract
18F-1 exhibited a high specificity for the kidney, rapid renal excretion comparable to that of 131I-OIH and high in vivo radiochemical stability. Not only is 18F-1 a promising PET renal tracer, but it provides a route to the development of a pair of analogous 18F/99mTc renal imaging agents with almost identical structures and comparable pharmacokinetic properties. These promising in vivo results warrant subsequent evaluation in humans.
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![Re(CO)3([18F]FEDA), a novel 18F PET renal tracer: Radiosynthesis and preclinical evaluation](/preview/png/8457721.png "First Page Preview: Re(CO)3([18F]FEDA), a novel 18F PET renal tracer: Radiosynthesis and preclinical evaluation")
Authors
Malgorzata Lipowska, Nashwa Jarkas, Ronald J. Voll, Jonathon A. Nye, Jeffrey Klenc, Mark M. Goodman, Andrew T. Taylor,