| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457770 | Nuclear Medicine and Biology | 2018 | 37 Pages |
Abstract
[64Cu]-DOTHA2-PEG-RM26 allows visualization of prostate tumors by PET imaging. DOTHA2 enables fast 64Cu chelation under mild condition, and as such could be used advantageously for the development of other 64Cu-labeled peptide-derived PET tracers.
Keywords
NHSN-hydroxy-succinimide%ID/gGastrin releasing peptide receptorTBQDiamsarTriisopropylsilaneDIEADOTACH3CNBFCSGRPRLC-MSTFATLCDMFPBSDCMEDCHEPES1-ethyl-3-(3-dimethylaminopropyl)carbodiimide hydrochloride64CuBSAN,N-diisopropylethylaminebovine serum albuminAcetonitrileTrifluoroacetic acidisopropyl alcoholBombesinPET imagingPositron emission tomographyDichloromethaneProstate cancerBBNLiquid chromatography-mass spectrometryPhosphate-buffered salineTIPSNOTAHATUPETthin layer chromatographyhigh performance liquid chromatographyHPLCBifunctional chelates
Related Topics
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Biochemistry, Genetics and Molecular Biology
Cancer Research
![Evaluation of a novel GRPR antagonist for prostate cancer PET imaging: [64Cu]-DOTHA2-PEG-RM26](/preview/png/8457770.png "First Page Preview: Evaluation of a novel GRPR antagonist for prostate cancer PET imaging: [64Cu]-DOTHA2-PEG-RM26")
Authors
Nematallah Mansour, Michel Paquette, Samia Ait-Mohand, Véronique Dumulon-Perreault, Brigitte Guérin,