| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457823 | Nuclear Medicine and Biology | 2013 | 6 Pages |
Abstract
An improved radiolabeling method by a SPE purification for preparation of [18F]FPBM, 1, was developed. The results suggest that it is feasible to use this labeling method to prepare [18F]FPBM, 1, without affecting in vivo SERT binding.
Keywords
5-HTPET imaging agentDASB18FADAMStriatumSPECTThalamussubstantia nigrasingle photon emission computed tomographyPositron emission tomographySERTCerSerotoninserotonin transporterCerebellumBrainHIPSelective serotonin reuptake inhibitorSSRIMediodorsal thalamic nucleusventrolateral thalamic nucleuscaudate nucleusdorsal raphe nucleusmedial amygdaloid nucleusdorsomedial hypothalamic nucleusHippocampusPETinternal capsuleGlobus pallidus
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![An improved preparation of [18F]FPBM: A potential serotonin transporter (SERT) imaging agent](/preview/png/8457823.png "First Page Preview: An improved preparation of [18F]FPBM: A potential serotonin transporter (SERT) imaging agent")
Authors
Lin Zhu, Genxun Li, Seok Rye Choi, Karl Plössl, Piu Chan, Hongwen Qiao, Zhihao Zha, Hank F. Kung,