| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457836 | Nuclear Medicine and Biology | 2013 | 7 Pages |
Abstract
The incorporated MAL linkage in [64Cu]NODAGA-MAL-exendin-4 was unable to reduce kidney radioactivity levels, compared to [64Cu]NODAGA-exendin-4. The applicability of metabolizable linkages in the design of kidney-saving exendin-4 analogs requires further investigation.
Keywords
Related Topics
Life Sciences
Biochemistry, Genetics and Molecular Biology
Cancer Research
![Synthesis and preclinical characterization of [64Cu]NODAGA-MAL-exendin-4 with a Nε-maleoyl-l-lysyl-glycine linkage](/preview/png/8457836.png "First Page Preview: Synthesis and preclinical characterization of [64Cu]NODAGA-MAL-exendin-4 with a Nε-maleoyl-l-lysyl-glycine linkage")
Authors
Cheng-Bin Yim, Kirsi Mikkola, Veronica Fagerholm, Viki-Veikko Elomaa, Tamiko Ishizu, Johan Rajander, Joern Schlesinger, Anne Roivainen, Pirjo Nuutila, Olof Solin,