| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457891 | Pathology - Research and Practice | 2018 | 7 Pages |
Abstract
The performance of Nrf2 is designed in colonic tissue of patients with UC. Environmental effects trigger innate immune system to produce ROS and inflammatory mediators. IL-17 can be released in response to Th-17 activation. phase II antioxidant genes such as PRDX1 and GST-A4 is induced as a result of the Nrf2 activation.
Keywords
nuclear factor erythroid 2 related factor 2HMOX-1Heme oxygenase-1IL-17APE1IBDNrf2DSSPrdx14-HNEapurinic/apyrimidinic endonucleaseMAPKROSinterleukin-17COPDChronic obstructive pulmonary diseaseinflammatory bowel diseasestrans-4-Hydroxy-2-nonenalOxidative stressIntestinal epithelial cellsdextran sodium sulfatePeroxiredoxin-1mitogen-activated protein kinaseIECUlcerative colitisReactive oxygen species
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Authors
Milad Sabzevary-Ghahfarokhi, Mojtaba Shohan, Hedayatollah Shirzad, Ghorbanali Rahimian, Amin Soltani, Mahdi Ghatreh-Samani, Fatemeh Deris, Nader Bagheri, Mohammedhadi Shafigh, Kamran Tahmasbi,