| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457925 | Pathology - Research and Practice | 2018 | 9 Pages |
Abstract
Analysis of DAPK1 gene promoter by quantitative pyrosequencing provided more detailed information of methylation status of CpG sites. DAPK1 methylation level is associated with gliomas clinical features and outcomes. Interestingly, the hypermethylation at site â1527 or together with site â1543 indicated good sensitivity of postoperative therapies, especially radiotherapy. Thus, site specifically analysis of DAPK1 methylation may be a valuable diagnostic and prognostic estimation for gliomas.
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Authors
Xinru Li, Jun Pu, Jiaxin Liu, Yijun Chen, Yu Li, Peng Hou, Bingyin Shi, Qi Yang,