| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8457974 | Pathology - Research and Practice | 2018 | 9 Pages |
Abstract
In conclusion, simultaneous analysis of TRAIL pathway membrane components, pointed towards a significant deregulation of mRNA expression in colorectal tumours. Death receptor overexpression was an indicator of a less aggressive phenotype. The multiple expression patterns of TRAIL pathway components in colorectal tumours underscore the importance of patient selection in order to achieve maximum efficiency with TRAIL targeted therapy.
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Authors
Spyridon Tsikalakis, Ilenia Chatziandreou, Nikolaos V. Michalopoulos, Georgios E. Theodoropoulos, Stratigoula Sakellariou, Penelope Korkolopoulou, Efstratios Patsouris, Angelica A. Saetta,