Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8459157 | Radiotherapy and Oncology | 2018 | 6 Pages |
Abstract
In resting tumour cells, glucose starvation combined with irradiation resulted in the impairment of late DSB repair and the reduction of clonogenic survival, which was associated with disrupted radiation-induced histone acetylation. However, in normal cells, DNA repair and radiosensitivity were not affected by glucose depletion.
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Authors
Rena Ampferl, Hans Peter Rodemann, Claus Mayer, Tobias Tim Alexander Höfling, Klaus Dittmann,