| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8459435 | Radiotherapy and Oncology | 2017 | 4 Pages |
Abstract
Association of heart dose and overall survival was investigated in a cohort including 469 locally-advanced NSCLC patients receiving daily low-dose hypofractionated chemo-radiotherapy. Significant associations were found over a range of dose parameters. Multivariate analysis showed significant associations of heart_V2Gy:HR = 1.007%â1 (95% CI:1.002-1.013; p = 0.006), age:HR = 1.026 yearâ1 (1.011-1.042; p = 0.001) and GTV volume:HR = 1.001 ccâ1 (1.000-1.002; p = 0.006) with overall survival.
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Authors
Barbara Stam, Erik van der Bijl, Judi van Diessen, Maddalena M.G. Rossi, Angela Tijhuis, José S.A. Belderbos, Eugène Damen, Jan-Jakob Sonke,