| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8459480 | Radiotherapy and Oncology | 2017 | 7 Pages |
Abstract
For the DGKA enhancer, we show that BET-bromodomain inhibitors can alter the epigenetic landscape of fibroblasts, thus counteracting profibrotic transcriptional events. Interference with epigenetic patterns of fibrosis predisposition may provide novel preventive therapies that improve radiotherapy.
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Authors
Gintvile Valinciute, Christoph Weigel, Marlon R. Veldwijk, Christopher C. Oakes, Carsten Herskind, Frederik Wenz, Christoph Plass, Peter Schmezer, Odilia Popanda,