Article ID Journal Published Year Pages File Type
8459503 Radiotherapy and Oncology 2016 6 Pages PDF
Abstract
CTVHR dose of ⩾85 Gy (D90) delivered in 7 weeks provides 3-year local control rates of >94% in limited size CTVHR (20 cm3), >93% in intermediate size (30 cm3) and >86% in large size (70 cm3) CTVHR. CTVIR and GTVres dose of ⩾60 Gy and ⩾95 Gy (D98) leads to similar local control. A dose of 5 Gy (CTVHR) is required to compensate an increase of OTT by one week. Increased CTVHR volume by 10 cm3 requires additional 5 Gy for equivalent local control.
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