| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8459655 | Radiotherapy and Oncology | 2011 | 5 Pages |
Abstract
This work suggests that GNP radiosensitisation is driven by inhomogeneities in dose on the nanoscale, rather than changes in dose over the entire cell, which may contribute to the similar radiosensitisation observed in megavoltage and kilovoltage experiments. The short range of these inhomogeneities and the variation in enhancement in different cells suggests sub-cellular localisation is important in determining GNP radiosensitisation.
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Authors
Stephen J. McMahon, Wendy B. Hyland, Mark F. Muir, Jonathan A. Coulter, Suneil Jain, Karl T. Butterworth, Giuseppe Schettino, Glenn R. Dickson, Alan R. Hounsell, Joe M. O'Sullivan, Kevin M. Prise, David G. Hirst, Fred J. Currell,