Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8459781 | Seminars in Oncology | 2017 | 16 Pages |
Abstract
NAC as a single agent reduces MCT4 stromal expression, which is a marker of glycolysis in breast cancer with reduced carcinoma cell proliferation. This study suggests that modulating metabolism in the tumor microenvironment has the potential to impact breast cancer proliferation.
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Authors
Daniel Monti, Federica Sotgia, Diana Whitaker-Menezes, Madalina Tuluc, Ruth Birbe, Adam Berger, Melissa Lazar, Paolo Cotzia, Rossitza Draganova-Tacheva, Zhao Lin, Marina Domingo-Vidal, Andrew Newberg, Michael P. Lisanti, Ubaldo Martinez-Outschoorn,