| Article ID | Journal | Published Year | Pages | File Type |
|---|---|---|---|---|
| 8460228 | Annals of Anatomy - Anatomischer Anzeiger | 2018 | 36 Pages |
Abstract
The DSCMs obtained in this work constitutes favorable structure- and growth factors providing a microenvironment which is very similar to that of native ECM, which results in enhanced biological potential of the MSCs and responsiveness to the induction of differentiation. We found differences between ascorbic derived-DSCMs and chondrogenic derived DSCMs. Our results suggest that the cell source used to produce DSCMs is highly related to the bioactive characteristics of DSCMs.
Keywords
FBSAggrecanTGFβ1CDMSSVFBMSCsMSCstransforming growth factor β 1adipose tissue derived mesenchymal stem cellsDMEMACANASCsadipose derived mesenchymal stem cellsCPCECMBSADulbecco’s modified Eagle mediumbovine serum albuminHyaluronic acidbeta actinCell proliferation and differentiationfetal bovine serumMesenchymal stem cellsbone marrow mesenchymal stem cellsDecellularized matrixExtracellular matrixGrowth mediumSEMScanning electron microscopyStromal vascular fraction
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Authors
S. Pérez-Castrillo, M.L. González-Fernández, M.E. López-González, V. Villar-Suárez,