Changes in rat testis morphology and androgen receptor expression around the age of puberty

Androgen receptors should not be excluded as an effective factor on germ cells through its direct action on AR, clearly expressed in spermatogenic cells and its surge at the age of puberty. Studies and treatments should respect the AR expected levels according to age in other testicular cells as well. Sertoli cells show a linear increase of AR expression throughout life, while Leydig cells show a peak at the age of puberty.