Article ID | Journal | Published Year | Pages | File Type |
---|---|---|---|---|
8462578 | Annals of Anatomy - Anatomischer Anzeiger | 2009 | 12 Pages |
Abstract
For the latter approach, the potential of bioreactor technology was combined with the efficient Cytodex 3 strategy under controlled environmental conditions (pH-7.2, pO2-30% and temperature-37 °C); cell growth was more efficient, as shown by faster doubling time, higher growth rate and higher fold increase in cell concentration, when compared to spinner cultures. This study describes a robust bioprocess for the controlled expansion of adult PSC, representing an efficient starting point for the development of novel technologies for cell therapy.
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Authors
Margarida Serra, Catarina Brito, Sofia B. Leite, Erwin Gorjup, Hagen von Briesen, Manuel J.T. Carrondo, Paula M. Alves,